首页> 外文OA文献 >A series of N-terminal epitope tagged Hdh knock-in alleles expressing normal and mutant huntingtin: their application to understanding the effect of increasing the length of normal huntingtin’s polyglutamine stretch on CAG140 mouse model pathogenesis

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A series of N-terminal epitope tagged Hdh knock-in alleles expressing normal and mutant huntingtin: their application to understanding the effect of increasing the length of normal huntingtin’s polyglutamine stretch on CAG140 mouse model pathogenesis

机译：表达正常和突变亨廷顿蛋白的一系列N末端表位标记的 Hdh 敲入等位基因：它们在理解增加正常亨廷顿蛋白的聚谷氨酰胺延伸长度对CAG140小鼠模型发病机理的影响中的应用

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Zheng Shuqiu; Ghitani Nima; Blackburn Jessica S; Liu Jeh-Ping; Zeitlin Scott O;
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1. A series of N-terminal epitope tagged Hdh knock-in alleles expressing normal and mutant huntingtin: their application to understanding the effect of increasing the length of normal huntingtin’s polyglutamine stretch on CAG140 mouse model pa [J] . Shuqiu Zheng, Nima Ghitani, Jessica S Blackburn, Molecular brain . 2012 ,第2期

机译：表达正常和突变亨廷顿蛋白的一系列N末端表位标记的Hdh敲入等位基因：它们在理解增加正常亨廷顿蛋白多谷氨酰胺延伸长度对CAG140小鼠模型pa的影响中的应用
2. Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. [J] . Chan EY, Luthi Carter R, Strand A, Human Molecular Genetics . 2002 ,第17期

机译：亨廷顿氏病蛋白模型中增加的亨廷顿蛋白长度减少了聚谷氨酰胺诱导的基因表达变化的次数。
3. Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length. [J] . de Almeida LP, Ross CA, Zala D, The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2002 ,第9期

机译：慢病毒介导的大鼠纹状体中亨廷顿蛋白突变体的递送诱导了由多谷氨酰胺重复序列大小，亨廷顿蛋白表达水平和蛋白质长度调节的选择性神经病理学。
4. A series of N-terminal epitope tagged Hdh knock-in alleles expressing normal and mutant huntingtin: their application to understanding the effect of increasing the length of normal huntingtin’s polyglutamine stretch on CAG140 mouse model pathogenesis [O] . Shuqiu Zheng, Nima Ghitani, Jessica S Blackburn, 2012

机译：表达正常和突变亨廷顿蛋白的一系列N末端表位标记的Hdh敲入等位基因：它们在了解增加正常亨廷顿蛋白的聚谷氨酰胺延伸长度对CAG140小鼠模型发病机理的影响中的应用
5. A series of N-terminal epitope tagged Hdh knock-in alleles expressing normal and mutant huntingtin: their application to understanding the effect of increasing the length of normal huntingtin’s polyglutamine stretch on CAG140 mouse model pathogenesis [O] . Shuqiu Zheng, Nima Ghitani, Jessica S Blackburn, 2012

机译：表达正常和突变亨廷顿蛋白的一系列N末端表位标记的Hdh敲入等位基因：它们在了解增加正常亨廷顿蛋白的聚谷氨酰胺延伸长度对CAG140小鼠模型发病机理的影响中的应用

A series of N-terminal epitope tagged Hdh knock-in alleles expressing normal and mutant huntingtin: their application to understanding the effect of increasing the length of normal huntingtin’s polyglutamine stretch on CAG140 mouse model pathogenesis

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